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SMILES: [#6]-[#8]-c1ccc(-[#6]-n2c(-[#7]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])nc(=O)n(-[#6]-c3cccc(-[#8]-[#6])c3)c2=O)cc1

InChI Key: InChIKey=BKDGWHBCHIFQHT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294587   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prokineticin receptor 1


(Homo sapiens (Human))		BDBM50294587
PNG
(1-(2-(5-(3-methoxybenzyl)-1-(4-methoxybenzyl)-4,6-...)
Show SMILES [#6]-[#8]-c1ccc(-[#6]-n2c(-[#7]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])nc(=O)n(-[#6]-c3cccc(-[#8]-[#6])c3)c2=O)cc1
Show InChI InChI=1S/C22H27N7O4/c1-32-17-8-6-15(7-9-17)13-28-20(26-11-10-25-19(23)24)27-21(30)29(22(28)31)14-16-4-3-5-18(12-16)33-2/h3-9,12H,10-11,13-14H2,1-2H3,(H4,23,24,25)(H,26,27,30)
MMDB

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KEGG

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Article
PubMed
n/an/a 3.69E+3n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 19: 2661-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.157
BindingDB Entry DOI: 10.7270/Q23N23DG
More data for this
Ligand-Target Pair