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SMILES: [#6]-[#8]-c1ccc(-[#6]-n2c(-[#7]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])nc(=O)n(-[#6]-c3ccc(cc3)C#N)c2=O)cc1

InChI Key: InChIKey=WBAZALTVRJWNBJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294592   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prokineticin receptor 1


(Homo sapiens (Human))		BDBM50294592
PNG
(1-(2-(5-(4-cyanobenzyl)-1-(4-methoxybenzyl)-4,6-di...)
Show SMILES [#6]-[#8]-c1ccc(-[#6]-n2c(-[#7]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])nc(=O)n(-[#6]-c3ccc(cc3)C#N)c2=O)cc1
Show InChI InChI=1S/C22H24N8O3/c1-33-18-8-6-17(7-9-18)13-29-20(27-11-10-26-19(24)25)28-21(31)30(22(29)32)14-16-4-2-15(12-23)3-5-16/h2-9H,10-11,13-14H2,1H3,(H4,24,25,26)(H,27,28,31)
MMDB

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n/an/a 318n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 19: 2661-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.157
BindingDB Entry DOI: 10.7270/Q23N23DG
More data for this
Ligand-Target Pair