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SMILES: [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#7]-c1nc(=O)n(-[#6]-c2ccc(Cl)cc2)c(=O)n1-[#6]-c1ccccc1

InChI Key: InChIKey=CTIXZRILXFCJHF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294595   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prokineticin receptor 1


(Homo sapiens (Human))		BDBM50294595
PNG
(1-(2-(1-benzyl-5-(4-chloro-2-methoxybenzyl)-4,6-di...)
Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#7]-c1nc(=O)n(-[#6]-c2ccc(Cl)cc2)c(=O)n1-[#6]-c1ccccc1
Show InChI InChI=1S/C20H22ClN7O2/c21-16-8-6-15(7-9-16)13-28-19(29)26-18(25-11-10-24-17(22)23)27(20(28)30)12-14-4-2-1-3-5-14/h1-9H,10-13H2,(H4,22,23,24)(H,25,26,29)
MMDB

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Similars
Article
PubMed
n/an/a 4.78E+3n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 19: 2661-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.157
BindingDB Entry DOI: 10.7270/Q23N23DG
More data for this
Ligand-Target Pair