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SMILES: [#6]-[#6]-[#6]-[#8]-c1ccc(-[#6]-n2c(-[#7]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])nc(=O)n(-[#6]-c3ccc(Cl)c(Cl)c3)c2=O)cc1

InChI Key: InChIKey=AKTFAMMOPZKRNY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294598   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prokineticin receptor 1


(Homo sapiens (Human))		BDBM50294598
PNG
(1-(2-(5-(3,4-dichlorobenzyl)-4,6-dioxo-1-(4-propox...)
Show SMILES [#6]-[#6]-[#6]-[#8]-c1ccc(-[#6]-n2c(-[#7]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])nc(=O)n(-[#6]-c3ccc(Cl)c(Cl)c3)c2=O)cc1
Show InChI InChI=1S/C23H27Cl2N7O3/c1-2-11-35-17-6-3-15(4-7-17)13-31-21(29-10-9-28-20(26)27)30-22(33)32(23(31)34)14-16-5-8-18(24)19(25)12-16/h3-8,12H,2,9-11,13-14H2,1H3,(H4,26,27,28)(H,29,30,33)
MMDB

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n/an/a 515n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 19: 2661-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.157
BindingDB Entry DOI: 10.7270/Q23N23DG
More data for this
Ligand-Target Pair