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SMILES: [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#7]-c1nc(=O)n(-[#6]-c2ccc(Cl)cc2)c(=O)n1-c1ccoc1

InChI Key: InChIKey=MECBNKHQRLUXQT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294602   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prokineticin receptor 1


(Homo sapiens (Human))		BDBM50294602
PNG
(1-(2-(5-(4-chlorobenzyl)-1-(furan-3-yl)-4,6-dioxo-...)
Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#7]-c1nc(=O)n(-[#6]-c2ccc(Cl)cc2)c(=O)n1-c1ccoc1
Show InChI InChI=1S/C17H18ClN7O3/c18-12-3-1-11(2-4-12)9-24-16(26)23-15(22-7-6-21-14(19)20)25(17(24)27)13-5-8-28-10-13/h1-5,8,10H,6-7,9H2,(H4,19,20,21)(H,22,23,26)
MMDB

NCI pathway
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KEGG

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.87E+3n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 19: 2661-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.157
BindingDB Entry DOI: 10.7270/Q23N23DG
More data for this
Ligand-Target Pair