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SMILES: [#6]-[#8]-c1ccc(-[#6]-n2c(=O)nc(-[#7]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])n(-[#6]-c3ccc(-[#8]-[#6])nc3)c2=O)cc1

InChI Key: InChIKey=RYSVUBYTFQIRGS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294603   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prokineticin receptor 1


(Homo sapiens (Human))		BDBM50294603
PNG
(1-(2-(5-(4-methoxybenzyl)-1-((6-methoxypyridin-3-y...)
Show SMILES [#6]-[#8]-c1ccc(-[#6]-n2c(=O)nc(-[#7]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])n(-[#6]-c3ccc(-[#8]-[#6])nc3)c2=O)cc1
Show InChI InChI=1S/C21H26N8O4/c1-32-16-6-3-14(4-7-16)12-29-20(30)27-19(25-10-9-24-18(22)23)28(21(29)31)13-15-5-8-17(33-2)26-11-15/h3-8,11H,9-10,12-13H2,1-2H3,(H4,22,23,24)(H,25,27,30)
MMDB

NCI pathway
Reactome pathway
KEGG

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 51n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 19: 2661-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.157
BindingDB Entry DOI: 10.7270/Q23N23DG
More data for this
Ligand-Target Pair