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SMILES: [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#7]-c1nc(=O)n(-[#6]-c2ccc(Cl)c(Cl)c2)c(=O)n1-[#6]-c1ccc(-[#8]-[#6](F)F)cc1

InChI Key: InChIKey=WMMJRTQQCSFDOB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294604   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prokineticin receptor 1


(Homo sapiens (Human))		BDBM50294604
PNG
(1-(2-(5-(3,4-dichlorobenzyl)-1-(4-(difluoromethoxy...)
Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#7]-c1nc(=O)n(-[#6]-c2ccc(Cl)c(Cl)c2)c(=O)n1-[#6]-c1ccc(-[#8]-[#6](F)F)cc1
Show InChI InChI=1S/C21H21Cl2F2N7O3/c22-15-6-3-13(9-16(15)23)11-32-20(33)30-19(29-8-7-28-18(26)27)31(21(32)34)10-12-1-4-14(5-2-12)35-17(24)25/h1-6,9,17H,7-8,10-11H2,(H4,26,27,28)(H,29,30,33)
MMDB

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n/an/a 47n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 19: 2661-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.157
BindingDB Entry DOI: 10.7270/Q23N23DG
More data for this
Ligand-Target Pair