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SMILES: [#6]-[#8]-c1ccc(-[#6]-n2c(-[#7]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])nc(=O)n(-[#6]-c3ccccc3)c2=O)cc1

InChI Key: InChIKey=UKQPBTRODNJZGL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294606   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prokineticin receptor 1


(Homo sapiens (Human))		BDBM50294606
PNG
(1-(2-(5-benzyl-1-(4-methoxybenzyl)-4,6-dioxo-1,4,5...)
Show SMILES [#6]-[#8]-c1ccc(-[#6]-n2c(-[#7]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])nc(=O)n(-[#6]-c3ccccc3)c2=O)cc1
Show InChI InChI=1S/C21H25N7O3/c1-31-17-9-7-16(8-10-17)13-27-19(25-12-11-24-18(22)23)26-20(29)28(21(27)30)14-15-5-3-2-4-6-15/h2-10H,11-14H2,1H3,(H4,22,23,24)(H,25,26,29)
MMDB

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Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 19: 2661-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.157
BindingDB Entry DOI: 10.7270/Q23N23DG
More data for this
Ligand-Target Pair