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SMILES: [#6]-[#8]-c1ccc(-[#6]-n2c(-[#7]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])nc(=O)n(-[#6]-[#6]-c3ccccc3)c2=O)cc1

InChI Key: InChIKey=QBDOFAGOTWCKQB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294607   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prokineticin receptor 1


(Homo sapiens (Human))		BDBM50294607
PNG
(1-(2-(1-(4-methoxybenzyl)-4,6-dioxo-5-phenethyl-1,...)
Show SMILES [#6]-[#8]-c1ccc(-[#6]-n2c(-[#7]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])nc(=O)n(-[#6]-[#6]-c3ccccc3)c2=O)cc1
Show InChI InChI=1S/C22H27N7O3/c1-32-18-9-7-17(8-10-18)15-29-20(26-13-12-25-19(23)24)27-21(30)28(22(29)31)14-11-16-5-3-2-4-6-16/h2-10H,11-15H2,1H3,(H4,23,24,25)(H,26,27,30)
MMDB

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Similars
Article
PubMed
n/an/a 2.50E+3n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 19: 2661-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.157
BindingDB Entry DOI: 10.7270/Q23N23DG
More data for this
Ligand-Target Pair