BDBM50295226 11-(2-chloro-6-fluorophenyl)-8-methyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one::CHEMBL556898

SMILES: Cc1ccc2N=C3CCCC(=O)C3C(Nc2c1)c1c(F)cccc1Cl

InChI Key: InChIKey=SWZGDUAWMLWJDS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295226   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NMBR (Homo sapiens (Human))	BDBM50295226 (11-(2-chloro-6-fluorophenyl)-8-methyl-2,3,4,5,10,1...) Show SMILES Cc1ccc2N=C3CCCC(=O)C3C(Nc2c1)c1c(F)cccc1Cl |t:5| Show InChI InChI=1S/C20H18ClFN2O/c1-11-8-9-14-16(10-11)24-20(18-12(21)4-2-5-13(18)22)19-15(23-14)6-3-7-17(19)25/h2,4-5,8-10,19-20,24H,3,6-7H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cells				Bioorg Med Chem Lett 19: 4264-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.124 BindingDB Entry DOI: 10.7270/Q2C24WG8
					More data for this Ligand-Target Pair