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BDBM50295228 11-(2-chloro-6-fluorophenyl)-3-(furan-2-yl)-8-methyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one::CHEMBL562770

SMILES: Cc1ccc2N=C3CC(CC(=O)C3C(Nc2c1)c1c(F)cccc1Cl)c1ccco1

InChI Key: InChIKey=YXSNYFJSTBVWMJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295228   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
NMBR


(Homo sapiens (Human))		BDBM50295228
PNG
(11-(2-chloro-6-fluorophenyl)-3-(furan-2-yl)-8-meth...)
Show SMILES Cc1ccc2N=C3CC(CC(=O)C3C(Nc2c1)c1c(F)cccc1Cl)c1ccco1 |t:5|
Show InChI InChI=1S/C24H20ClFN2O2/c1-13-7-8-17-18(10-13)28-24(22-15(25)4-2-5-16(22)26)23-19(27-17)11-14(12-20(23)29)21-6-3-9-30-21/h2-10,14,23-24,28H,11-12H2,1H3
KEGG

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PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cells

Bioorg Med Chem Lett 19: 4264-7 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.124
BindingDB Entry DOI: 10.7270/Q2C24WG8
More data for this
Ligand-Target Pair