BDBM50295494 (R)-2-(7-(Ethoxycarbonylamino)dibenzo[b,d]thiophene-3-sulfonamido)-3-methylbutanoic Acid::CHEMBL562374
SMILES: CCOC(=O)Nc1ccc2c(c1)sc1cc(ccc21)S(=O)(=O)N[C@H](C(C)C)C(O)=O
InChI Key: InChIKey=ZURXLNWQPVEFOH-GOSISDBHSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Matrix metalloproteinase-12 (MMP12) (Homo sapiens (Human)) | BDBM50295494 ((R)-2-(7-(Ethoxycarbonylamino)dibenzo[b,d]thiophen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of human recombinant MMP12 | J Med Chem 52: 5408-19 (2009) Article DOI: 10.1021/jm900809r BindingDB Entry DOI: 10.7270/Q21J99SW | |||||||||||
More data for this Ligand-Target Pair |