BDBM50295496 (S)-2-(7-(Isopropoxycarbonylamino)dibenzo[b,d]thiophene-3-sulfonamido)-3-methylbutanoic Acid::CHEMBL559583

SMILES: CC(C)OC(=O)Nc1ccc2c(c1)sc1cc(ccc21)S(=O)(=O)N[C@@H](C(C)C)C(O)=O

InChI Key: InChIKey=WUJPOLIUEWWSHN-IBGZPJMESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295496   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50295496 ((S)-2-(7-(Isopropoxycarbonylamino)dibenzo[b,d]thio...) Show SMILES CC(C)OC(=O)Nc1ccc2c(c1)sc1cc(ccc21)S(=O)(=O)N[C@@H](C(C)C)C(O)=O |r| Show InChI InChI=1S/C21H24N2O6S2/c1-11(2)19(20(24)25)23-31(27,28)14-6-8-16-15-7-5-13(22-21(26)29-12(3)4)9-17(15)30-18(16)10-14/h5-12,19,23H,1-4H3,(H,22,26)(H,24,25)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP13				J Med Chem 52: 5408-19 (2009) Article DOI: 10.1021/jm900809r BindingDB Entry DOI: 10.7270/Q21J99SW
					More data for this Ligand-Target Pair
Matrix metalloproteinase-12 (MMP12) (Homo sapiens (Human))	BDBM50295496 ((S)-2-(7-(Isopropoxycarbonylamino)dibenzo[b,d]thio...) Show SMILES CC(C)OC(=O)Nc1ccc2c(c1)sc1cc(ccc21)S(=O)(=O)N[C@@H](C(C)C)C(O)=O |r| Show InChI InChI=1S/C21H24N2O6S2/c1-11(2)19(20(24)25)23-31(27,28)14-6-8-16-15-7-5-13(22-21(26)29-12(3)4)9-17(15)30-18(16)10-14/h5-12,19,23H,1-4H3,(H,22,26)(H,24,25)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP12				J Med Chem 52: 5408-19 (2009) Article DOI: 10.1021/jm900809r BindingDB Entry DOI: 10.7270/Q21J99SW
					More data for this Ligand-Target Pair