BDBM50295568 3,4-Dihydro-8-methyl-3-[2-(6-methylnaphthoyl)]-2H-pyrido[1,2-a]pyrimidine perchlorate::CHEMBL562458

SMILES: Cc1ccn2CC(CN[c+]2c1)C(=O)c1ccc2cc(C)ccc2c1

InChI Key: InChIKey=DJTIRUGMSOSCKU-UHFFFAOYSA-O

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric Oxide Synthase, inducible (Mus musculus (mouse))	BDBM50295568 (3,4-Dihydro-8-methyl-3-[2-(6-methylnaphthoyl)]-2H-...) Show SMILES Cc1ccn2CC(CN[c+]2c1)C(=O)c1ccc2cc(C)ccc2c1 Show InChI InChI=1S/C21H20N2O/c1-14-3-4-17-11-18(6-5-16(17)9-14)21(24)19-12-22-20-10-15(2)7-8-23(20)13-19/h3-11,19H,12-13H2,1-2H3/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of mouse iNOS expressed in insect Sf9 cells by competitive binding assay				Eur J Med Chem 44: 2877-87 (2009) Article DOI: 10.1016/j.ejmech.2008.12.007 BindingDB Entry DOI: 10.7270/Q2KD1ZV6
					More data for this Ligand-Target Pair
Nitric Oxide Synthase, inducible (Mus musculus (mouse))	BDBM50295568 (3,4-Dihydro-8-methyl-3-[2-(6-methylnaphthoyl)]-2H-...) Show SMILES Cc1ccn2CC(CN[c+]2c1)C(=O)c1ccc2cc(C)ccc2c1 Show InChI InChI=1S/C21H20N2O/c1-14-3-4-17-11-18(6-5-16(17)9-14)21(24)19-12-22-20-10-15(2)7-8-23(20)13-19/h3-11,19H,12-13H2,1-2H3/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radioactiv...				Eur J Med Chem 44: 2877-87 (2009) Article DOI: 10.1016/j.ejmech.2008.12.007 BindingDB Entry DOI: 10.7270/Q2KD1ZV6
					More data for this Ligand-Target Pair