BDBM50295569 3-[4'-(4''-Bromophenyl)benzoyl]-3,4-dihydro-6,8-dimethyl-2Hpyrido[1,2-a]pyrimidine perchlorate::CHEMBL556316

SMILES: Cc1cc(C)n2CC(CN[c+]2c1)C(=O)c1ccc(cc1)-c1ccc(Br)cc1

InChI Key: InChIKey=XSSPZNFANZSTAS-UHFFFAOYSA-O

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295569   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric Oxide Synthase, inducible (Mus musculus (mouse))	BDBM50295569 (3-[4'-(4''-Bromophenyl)benzoyl]-3,4-dihydro-6,8-di...) Show SMILES Cc1cc(C)n2CC(CN[c+]2c1)C(=O)c1ccc(cc1)-c1ccc(Br)cc1 Show InChI InChI=1S/C23H21BrN2O/c1-15-11-16(2)26-14-20(13-25-22(26)12-15)23(27)19-5-3-17(4-6-19)18-7-9-21(24)10-8-18/h3-12,20H,13-14H2,1-2H3/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radioactiv...				Eur J Med Chem 44: 2877-87 (2009) Article DOI: 10.1016/j.ejmech.2008.12.007 BindingDB Entry DOI: 10.7270/Q2KD1ZV6
					More data for this Ligand-Target Pair
Nitric Oxide Synthase, endothelial (Bos taurus (bovine))	BDBM50295569 (3-[4'-(4''-Bromophenyl)benzoyl]-3,4-dihydro-6,8-di...) Show SMILES Cc1cc(C)n2CC(CN[c+]2c1)C(=O)c1ccc(cc1)-c1ccc(Br)cc1 Show InChI InChI=1S/C23H21BrN2O/c1-15-11-16(2)26-14-20(13-25-22(26)12-15)23(27)19-5-3-17(4-6-19)18-7-9-21(24)10-8-18/h3-12,20H,13-14H2,1-2H3/p+1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.88E+5	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radioacti...				Eur J Med Chem 44: 2877-87 (2009) Article DOI: 10.1016/j.ejmech.2008.12.007 BindingDB Entry DOI: 10.7270/Q2KD1ZV6
					More data for this Ligand-Target Pair