BDBM50295576 4-chloro-N-(4-(2-(2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenylamino)-2-oxoethyl)thiazol-2-yl)benzamide::CHEMBL561983

SMILES: Fc1cc(ccc1NC(=O)Cc1csc(NC(=O)c2ccc(Cl)cc2)n1)-n1ccccc1=O

InChI Key: InChIKey=XDWOSSGQLPEBJH-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295576   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50295576 (4-chloro-N-(4-(2-(2-fluoro-4-(2-oxopyridin-1(2H)-y...) Show SMILES Fc1cc(ccc1NC(=O)Cc1csc(NC(=O)c2ccc(Cl)cc2)n1)-n1ccccc1=O Show InChI InChI=1S/C23H16ClFN4O3S/c24-15-6-4-14(5-7-15)22(32)28-23-26-16(13-33-23)11-20(30)27-19-9-8-17(12-18(19)25)29-10-2-1-3-21(29)31/h1-10,12-13H,11H2,(H,27,30)(H,26,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	112	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F Hoffmann - La Roche Ltd Curated by ChEMBL					Assay Description Binding affinity to factor 10a				Eur J Med Chem 44: 2787-95 (2009) Article DOI: 10.1016/j.ejmech.2008.12.025 BindingDB Entry DOI: 10.7270/Q2CV4HSP
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50295576 (4-chloro-N-(4-(2-(2-fluoro-4-(2-oxopyridin-1(2H)-y...) Show SMILES Fc1cc(ccc1NC(=O)Cc1csc(NC(=O)c2ccc(Cl)cc2)n1)-n1ccccc1=O Show InChI InChI=1S/C23H16ClFN4O3S/c24-15-6-4-14(5-7-15)22(32)28-23-26-16(13-33-23)11-20(30)27-19-9-8-17(12-18(19)25)29-10-2-1-3-21(29)31/h1-10,12-13H,11H2,(H,27,30)(H,26,28,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F Hoffmann - La Roche Ltd Curated by ChEMBL					Assay Description Binding affinity to thrombin				Eur J Med Chem 44: 2787-95 (2009) Article DOI: 10.1016/j.ejmech.2008.12.025 BindingDB Entry DOI: 10.7270/Q2CV4HSP
					More data for this Ligand-Target Pair