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SMILES: CN1CCC(CC1)N1CCN(CC1)C(=O)Cn1cnc(NC(=O)c2ccc(Cl)s2)n1

InChI Key: InChIKey=TXAAJVJNTQKPMH-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295582   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50295582
PNG
(4-chloro-N-(1-(2-(4-(1-methylpiperidin-4-yl)pipera...)
Show SMILES CN1CCC(CC1)N1CCN(CC1)C(=O)Cn1cnc(NC(=O)c2ccc(Cl)s2)n1
Show InChI InChI=1S/C19H26ClN7O2S/c1-24-6-4-14(5-7-24)25-8-10-26(11-9-25)17(28)12-27-13-21-19(23-27)22-18(29)15-2-3-16(20)30-15/h2-3,13-14H,4-12H2,1H3,(H,22,23,29)
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MMDB

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 175n/an/an/an/an/an/an/an/a



F Hoffmann - La Roche Ltd

Curated by ChEMBL


Assay Description
Binding affinity to factor 10a

Eur J Med Chem 44: 2787-95 (2009)


Article DOI: 10.1016/j.ejmech.2008.12.025
BindingDB Entry DOI: 10.7270/Q2CV4HSP
More data for this
Ligand-Target Pair