BDBM50295594 (+/-)-5-chloro-N-(4-cyclopropyl-1-(2-(2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenylamino)-2-oxoethyl)pyrrolidin-3-yl)thiophene-2-carboxamide::CHEMBL549696

SMILES: Fc1cc(ccc1NC(=O)CN1CC(NC(=O)c2ccc(Cl)s2)C(C1)C1CC1)-n1ccccc1=O

InChI Key: InChIKey=SSZSOJSKTSKNPE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295594   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50295594 ((+/-)-5-chloro-N-(4-cyclopropyl-1-(2-(2-fluoro-4-(...) Show SMILES Fc1cc(ccc1NC(=O)CN1CC(NC(=O)c2ccc(Cl)s2)C(C1)C1CC1)-n1ccccc1=O Show InChI InChI=1S/C25H24ClFN4O3S/c26-22-9-8-21(35-22)25(34)29-20-13-30(12-17(20)15-4-5-15)14-23(32)28-19-7-6-16(11-18(19)27)31-10-2-1-3-24(31)33/h1-3,6-11,15,17,20H,4-5,12-14H2,(H,28,32)(H,29,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F Hoffmann - La Roche Ltd Curated by ChEMBL					Assay Description Binding affinity to factor 10a				Eur J Med Chem 44: 2787-95 (2009) Article DOI: 10.1016/j.ejmech.2008.12.025 BindingDB Entry DOI: 10.7270/Q2CV4HSP
					More data for this Ligand-Target Pair