BDBM50295598 5-chloro-N-((3R,5S)-1-(2-(2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenylamino)-2-oxoethyl)-5-(pyrrolidin-1-ylmethyl)pyrrolidin-3-yl)thiophene-2-carboxamide::CHEMBL550103

SMILES: Fc1cc(ccc1NC(=O)CN1C[C@@H](C[C@H]1CN1CCCC1)NC(=O)c1ccc(Cl)s1)-n1ccccc1=O

InChI Key: InChIKey=GUAAWHKIGRPHKA-QUCCMNQESA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295598   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50295598 (5-chloro-N-((3R,5S)-1-(2-(2-fluoro-4-(2-oxopyridin...) Show SMILES Fc1cc(ccc1NC(=O)CN1C[C@@H](C[C@H]1CN1CCCC1)NC(=O)c1ccc(Cl)s1)-n1ccccc1=O |r| Show InChI InChI=1S/C27H29ClFN5O3S/c28-24-9-8-23(38-24)27(37)30-18-13-20(16-32-10-3-4-11-32)33(15-18)17-25(35)31-22-7-6-19(14-21(22)29)34-12-2-1-5-26(34)36/h1-2,5-9,12,14,18,20H,3-4,10-11,13,15-17H2,(H,30,37)(H,31,35)/t18-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	132	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F Hoffmann - La Roche Ltd Curated by ChEMBL					Assay Description Binding affinity to factor 10a				Eur J Med Chem 44: 2787-95 (2009) Article DOI: 10.1016/j.ejmech.2008.12.025 BindingDB Entry DOI: 10.7270/Q2CV4HSP
					More data for this Ligand-Target Pair