BDBM50295910 3-(5-Methoxy-1-(3-(1H-imidazol-1-yl)propyl)-1H-indol-3-yl)-4-(1H-pyrrolo[3,2-b]pyridin-1-yl)-1H-pyrrole-2,5-dione::CHEMBL561929

SMILES: COc1ccc2n(CCCn3ccnc3)cc(C3=C(C(=O)NC3=O)n3ccc4ncccc34)c2c1

InChI Key: InChIKey=PYHDPTGVFANSRA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295910   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50295910 (3-(5-Methoxy-1-(3-(1H-imidazol-1-yl)propyl)-1H-ind...) Show SMILES COc1ccc2n(CCCn3ccnc3)cc(C3=C(C(=O)NC3=O)n3ccc4ncccc34)c2c1 |t:18| Show InChI InChI=1S/C26H22N6O3/c1-35-17-5-6-21-18(14-17)19(15-31(21)11-3-10-30-13-9-27-16-30)23-24(26(34)29-25(23)33)32-12-7-20-22(32)4-2-8-28-20/h2,4-9,12-16H,3,10-11H2,1H3,(H,29,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of recombinant GST-GSK3beta expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem 17: 4302-12 (2009) Article DOI: 10.1016/j.bmc.2009.05.031 BindingDB Entry DOI: 10.7270/Q2XP750M
					More data for this Ligand-Target Pair