BDBM50295912 3-(6-Fluoro-1-(3-(1H-imidazol-1-yl)propyl)-1H-indol-3-yl)-4-(1H-pyrrolo[3,2-b]pyridin-1-yl)-1H-pyrrole-2,5-dione::CHEMBL550925

SMILES: Fc1ccc2c(cn(CCCn3ccnc3)c2c1)C1=C(C(=O)NC1=O)n1ccc2ncccc12

InChI Key: InChIKey=BJMTXIZQCDGXRJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50295912 (3-(6-Fluoro-1-(3-(1H-imidazol-1-yl)propyl)-1H-indo...) Show SMILES Fc1ccc2c(cn(CCCn3ccnc3)c2c1)C1=C(C(=O)NC1=O)n1ccc2ncccc12 |t:21| Show InChI InChI=1S/C25H19FN6O2/c26-16-4-5-17-18(14-31(21(17)13-16)10-2-9-30-12-8-27-15-30)22-23(25(34)29-24(22)33)32-11-6-19-20(32)3-1-7-28-19/h1,3-8,11-15H,2,9-10H2,(H,29,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of recombinant GST-GSK3beta expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem 17: 4302-12 (2009) Article DOI: 10.1016/j.bmc.2009.05.031 BindingDB Entry DOI: 10.7270/Q2XP750M
					More data for this Ligand-Target Pair