BDBM50295913 3-(1-(3-(Dimethylamino)propyl)-1H-indol-3-yl)-4-(1Hpyrrolo[3,2-b]pyridin-1-yl)-1H-pyrrole-2,5-dione::CHEMBL559040

SMILES: CN(C)CCCn1cc(C2=C(C(=O)NC2=O)n2ccc3ncccc23)c2ccccc12

InChI Key: InChIKey=AYNGABNXYBWCBY-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295913   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50295913 (3-(1-(3-(Dimethylamino)propyl)-1H-indol-3-yl)-4-(1...) Show SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)n2ccc3ncccc23)c2ccccc12 |t:9| Show InChI InChI=1S/C24H23N5O2/c1-27(2)12-6-13-28-15-17(16-7-3-4-8-19(16)28)21-22(24(31)26-23(21)30)29-14-10-18-20(29)9-5-11-25-18/h3-5,7-11,14-15H,6,12-13H2,1-2H3,(H,26,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of recombinant GST-GSK3beta expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem 17: 4302-12 (2009) Article DOI: 10.1016/j.bmc.2009.05.031 BindingDB Entry DOI: 10.7270/Q2XP750M
					More data for this Ligand-Target Pair