BDBM50295918 3-(1-(3-Morpholinopropyl)-1H-indol-3-yl)-4-(1Hpyrrolo[3,2-b]pyridin-1-yl)-1H-pyrrole-2,5-dione::CHEMBL564437

SMILES: O=C1NC(=O)C(=C1c1cn(CCCN2CCOCC2)c2ccccc12)n1ccc2ncccc12

InChI Key: InChIKey=VFGRWUHPZBGVGC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295918   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50295918 (3-(1-(3-Morpholinopropyl)-1H-indol-3-yl)-4-(1Hpyrr...) Show SMILES O=C1NC(=O)C(=C1c1cn(CCCN2CCOCC2)c2ccccc12)n1ccc2ncccc12 |c:5| Show InChI InChI=1S/C26H25N5O3/c32-25-23(24(26(33)28-25)31-12-8-20-22(31)7-3-9-27-20)19-17-30(21-6-2-1-5-18(19)21)11-4-10-29-13-15-34-16-14-29/h1-3,5-9,12,17H,4,10-11,13-16H2,(H,28,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of recombinant GST-GSK3beta expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem 17: 4302-12 (2009) Article DOI: 10.1016/j.bmc.2009.05.031 BindingDB Entry DOI: 10.7270/Q2XP750M
					More data for this Ligand-Target Pair