BDBM50295925 (E)-3'-Propenyl)-5-(2-propenyl)-biphenyl-2,4'-diol::CHEMBL569136::Magreth-4
SMILES: C\C=C\c1cc(ccc1O)-c1cc(CC=C)ccc1O
InChI Key: InChIKey=MHZPQXNOHIORFI-GQCTYLIASA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50295925 ((E)-3'-Propenyl)-5-(2-propenyl)-biphenyl-2,4'-diol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bern | Assay Description Binding assay with hCB1 and hCB2 receptors. | Chem Biol 18: 1053-64 (2011) Article DOI: 10.1016/j.chembiol.2011.05.012 BindingDB Entry DOI: 10.7270/Q27W69PQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50295925 ((E)-3'-Propenyl)-5-(2-propenyl)-biphenyl-2,4'-diol...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bern | Assay Description Binding assay with hCB1 and hCB2 receptors. | Chem Biol 18: 1053-64 (2011) Article DOI: 10.1016/j.chembiol.2011.05.012 BindingDB Entry DOI: 10.7270/Q27W69PQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep)) | BDBM50295925 ((E)-3'-Propenyl)-5-(2-propenyl)-biphenyl-2,4'-diol...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Karl-Franzens-Universit£t Graz Curated by ChEMBL | Assay Description Inhibition of COX1 in ram seminal vesicle by enzyme immunoassay | Bioorg Med Chem 17: 4459-65 (2009) Article DOI: 10.1016/j.bmc.2009.05.018 BindingDB Entry DOI: 10.7270/Q2SX6D9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase (Cyclooxygenase-2) (Ovis aries (Sheep)) | BDBM50295925 ((E)-3'-Propenyl)-5-(2-propenyl)-biphenyl-2,4'-diol...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Karl-Franzens-Universit£t Graz Curated by ChEMBL | Assay Description Inhibition of COX2 in sheep placental vesicle by enzyme immunoassay | Bioorg Med Chem 17: 4459-65 (2009) Article DOI: 10.1016/j.bmc.2009.05.018 BindingDB Entry DOI: 10.7270/Q2SX6D9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Homo sapiens (Human)) | BDBM50295925 ((E)-3'-Propenyl)-5-(2-propenyl)-biphenyl-2,4'-diol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Karl-Franzens-Universit£t Graz Curated by ChEMBL | Assay Description Inhibition of 5LOX-mediated LTB4 formation in stimulated human polymorphonuclear leukocytes | Bioorg Med Chem 17: 4459-65 (2009) Article DOI: 10.1016/j.bmc.2009.05.018 BindingDB Entry DOI: 10.7270/Q2SX6D9B | |||||||||||
More data for this Ligand-Target Pair |