null

SMILES: CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc[nH]c1)C(=O)Nc1[nH]nc2c1CN(C2(C)C)S(=O)(=O)c1cc(F)cc(F)c1

InChI Key: InChIKey=JLIMOKFGZNPROX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296356   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50296356 (CHEMBL541762 | N-(5-(5-(3,5-difluorophenylsulfonyl...) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc[nH]c1)C(=O)Nc1[nH]nc2c1CN(C2(C)C)S(=O)(=O)c1cc(F)cc(F)c1 Show InChI InChI=1S/C30H32F2N8O4S/c1-30(2)26-23(17-40(30)45(43,44)22-14-20(31)13-21(32)15-22)27(37-36-26)35-28(41)18-4-5-25(39-10-8-38(3)9-11-39)24(12-18)34-29(42)19-6-7-33-16-19/h4-7,12-16,33H,8-11,17H2,1-3H3,(H,34,42)(H2,35,36,37,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
University of South Florida Curated by ChEMBL					Assay Description Inhibition of GST-tagged human IGF1R expressed in baculovirus-infected Sf21 cells by scintillation proximity assay				J Med Chem 52: 4981-5004 (2010) Article DOI: 10.1021/jm9002395 BindingDB Entry DOI: 10.7270/Q2P84CTD
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50296356 (CHEMBL541762 | N-(5-(5-(3,5-difluorophenylsulfonyl...) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc[nH]c1)C(=O)Nc1[nH]nc2c1CN(C2(C)C)S(=O)(=O)c1cc(F)cc(F)c1 Show InChI InChI=1S/C30H32F2N8O4S/c1-30(2)26-23(17-40(30)45(43,44)22-14-20(31)13-21(32)15-22)27(37-36-26)35-28(41)18-4-5-25(39-10-8-38(3)9-11-39)24(12-18)34-29(42)19-6-7-33-16-19/h4-7,12-16,33H,8-11,17H2,1-3H3,(H,34,42)(H2,35,36,37,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of South Florida Curated by ChEMBL					Assay Description Inhibition of IGF1R in IGF1-stimulated human MCF7 cells by western blot analysis				J Med Chem 52: 4981-5004 (2010) Article DOI: 10.1021/jm9002395 BindingDB Entry DOI: 10.7270/Q2P84CTD
					More data for this Ligand-Target Pair