BDBM50296425 2-(pyridin-4-ylmethylamino)-1-(4-tosylpiperazin-1-yl)ethanone::CHEMBL550115

SMILES: Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CNCc1ccncc1

InChI Key: InChIKey=VUVYNZSKGLHGTE-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50296425   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carboxypeptidase B (Helicoverpa zea (Corn earworm moth) (Heliothis zea...)	BDBM50296425 (2-(pyridin-4-ylmethylamino)-1-(4-tosylpiperazin-1-...) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CNCc1ccncc1 Show InChI InChI=1S/C19H24N4O3S/c1-16-2-4-18(5-3-16)27(25,26)23-12-10-22(11-13-23)19(24)15-21-14-17-6-8-20-9-7-17/h2-9,21H,10-15H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Aut£noma de Barcelona Curated by ChEMBL					Assay Description Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system				Eur J Med Chem 44: 3266-71 (2009) Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4
					More data for this Ligand-Target Pair
Carboxypeptidase A1 (Bos taurus (bovine))	BDBM50296425 (2-(pyridin-4-ylmethylamino)-1-(4-tosylpiperazin-1-...) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CNCc1ccncc1 Show InChI InChI=1S/C19H24N4O3S/c1-16-2-4-18(5-3-16)27(25,26)23-12-10-22(11-13-23)19(24)15-21-14-17-6-8-20-9-7-17/h2-9,21H,10-15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Aut£noma de Barcelona Curated by ChEMBL					Assay Description Inhibition of bovine carboxypeptidase A1				Eur J Med Chem 44: 3266-71 (2009) Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4
					More data for this Ligand-Target Pair
Thrombin-activatable fibrinolysis (TAFI) (Homo sapiens (Human))	BDBM50296425 (2-(pyridin-4-ylmethylamino)-1-(4-tosylpiperazin-1-...) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CNCc1ccncc1 Show InChI InChI=1S/C19H24N4O3S/c1-16-2-4-18(5-3-16)27(25,26)23-12-10-22(11-13-23)19(24)15-21-14-17-6-8-20-9-7-17/h2-9,21H,10-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.64E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Aut£noma de Barcelona Curated by ChEMBL					Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system				Eur J Med Chem 44: 3266-71 (2009) Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4
					More data for this Ligand-Target Pair