BDBM50296430 CHEMBL563306::N-(3-methoxybenzyl)-3-methyl-N-(pyridin-3-ylmethyl)-4-(1H-tetrazol-1-yl)benzenesulfonamide

SMILES: COc1cccc(CN(Cc2cccnc2)S(=O)(=O)c2ccc(c(C)c2)-n2cnnn2)c1

InChI Key: InChIKey=DSUVCQQLIVKLSM-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50296430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombin-activatable fibrinolysis (TAFI) (Homo sapiens (Human))	BDBM50296430 (CHEMBL563306 | N-(3-methoxybenzyl)-3-methyl-N-(pyr...) Show SMILES COc1cccc(CN(Cc2cccnc2)S(=O)(=O)c2ccc(c(C)c2)-n2cnnn2)c1 Show InChI InChI=1S/C22H22N6O3S/c1-17-11-21(8-9-22(17)28-16-24-25-26-28)32(29,30)27(15-19-6-4-10-23-13-19)14-18-5-3-7-20(12-18)31-2/h3-13,16H,14-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.39E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Aut£noma de Barcelona Curated by ChEMBL					Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system				Eur J Med Chem 44: 3266-71 (2009) Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4
					More data for this Ligand-Target Pair
Carboxypeptidase B (Helicoverpa zea (Corn earworm moth) (Heliothis zea...)	BDBM50296430 (CHEMBL563306 | N-(3-methoxybenzyl)-3-methyl-N-(pyr...) Show SMILES COc1cccc(CN(Cc2cccnc2)S(=O)(=O)c2ccc(c(C)c2)-n2cnnn2)c1 Show InChI InChI=1S/C22H22N6O3S/c1-17-11-21(8-9-22(17)28-16-24-25-26-28)32(29,30)27(15-19-6-4-10-23-13-19)14-18-5-3-7-20(12-18)31-2/h3-13,16H,14-15H2,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.84E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Aut£noma de Barcelona Curated by ChEMBL					Assay Description Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system				Eur J Med Chem 44: 3266-71 (2009) Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4
					More data for this Ligand-Target Pair
Carboxypeptidase A1 (Bos taurus (bovine))	BDBM50296430 (CHEMBL563306 | N-(3-methoxybenzyl)-3-methyl-N-(pyr...) Show SMILES COc1cccc(CN(Cc2cccnc2)S(=O)(=O)c2ccc(c(C)c2)-n2cnnn2)c1 Show InChI InChI=1S/C22H22N6O3S/c1-17-11-21(8-9-22(17)28-16-24-25-26-28)32(29,30)27(15-19-6-4-10-23-13-19)14-18-5-3-7-20(12-18)31-2/h3-13,16H,14-15H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.48E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Aut£noma de Barcelona Curated by ChEMBL					Assay Description Inhibition of bovine carboxypeptidase A1				Eur J Med Chem 44: 3266-71 (2009) Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4
					More data for this Ligand-Target Pair