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SMILES: Cc1nc(co1)C(=O)NC[C@@H](NS(=O)(=O)c1c(C)cc(C)cc1C)C(O)=O

InChI Key: InChIKey=LPYZHGQSYMJULB-CYBMUJFWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296609   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrin alpha-V


(Homo sapiens (Human))		BDBM50296609
PNG
((R)-3-(2-methyloxazole-4-carboxamido)-2-(2,4,6-tri...)
Show SMILES Cc1nc(co1)C(=O)NC[C@@H](NS(=O)(=O)c1c(C)cc(C)cc1C)C(O)=O |r|
Show InChI InChI=1S/C17H21N3O6S/c1-9-5-10(2)15(11(3)6-9)27(24,25)20-13(17(22)23)7-18-16(21)14-8-26-12(4)19-14/h5-6,8,13,20H,7H2,1-4H3,(H,18,21)(H,22,23)/t13-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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DrugBank
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 41n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin

Bioorg Med Chem Lett 19: 4832-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ
More data for this
Ligand-Target Pair