BDBM50296721 CHEMBL550054::m-tolyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate

SMILES: Cc1cccc(OC(=O)N2CCN3CCC2CC3)c1

InChI Key: InChIKey=KBXCOZWHXPHSEU-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296721   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50296721 (CHEMBL550054 | m-tolyl 1,4-diazabicyclo[3.2.2]nona...) Show SMILES Cc1cccc(OC(=O)N2CCN3CCC2CC3)c1 |TLB:7:9:14.13:16.17,(23.73,2.25,;22.27,2.79,;22,4.31,;20.54,4.83,;19.36,3.84,;19.64,2.32,;18.46,1.33,;17.01,1.85,;16.73,3.37,;15.83,.86,;16.19,-.62,;15.18,.1,;13.8,.03,;13.72,1.74,;14.35,2.9,;14.41,1.47,;13.11,.77,;12.81,-.67,;21.08,1.79,)| Show InChI InChI=1S/C15H20N2O2/c1-12-3-2-4-14(11-12)19-15(18)17-10-9-16-7-5-13(17)6-8-16/h2-4,11,13H,5-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nAChR expressed in rat GH4C1 cells				Bioorg Med Chem Lett 19: 4747-51 (2009) Article DOI: 10.1016/j.bmcl.2009.06.059 BindingDB Entry DOI: 10.7270/Q21G0N69
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50296721 (CHEMBL550054 | m-tolyl 1,4-diazabicyclo[3.2.2]nona...) Show SMILES Cc1cccc(OC(=O)N2CCN3CCC2CC3)c1 |TLB:7:9:14.13:16.17,(23.73,2.25,;22.27,2.79,;22,4.31,;20.54,4.83,;19.36,3.84,;19.64,2.32,;18.46,1.33,;17.01,1.85,;16.73,3.37,;15.83,.86,;16.19,-.62,;15.18,.1,;13.8,.03,;13.72,1.74,;14.35,2.9,;14.41,1.47,;13.11,.77,;12.81,-.67,;21.08,1.79,)| Show InChI InChI=1S/C15H20N2O2/c1-12-3-2-4-14(11-12)19-15(18)17-10-9-16-7-5-13(17)6-8-16/h2-4,11,13H,5-10H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Displacement of L-[3H]Nicotine from alpha4beta2 nAChR in rat brain homogenate by rapid filtration method				Bioorg Med Chem Lett 19: 4747-51 (2009) Article DOI: 10.1016/j.bmcl.2009.06.059 BindingDB Entry DOI: 10.7270/Q21G0N69
					More data for this Ligand-Target Pair