BDBM50296867 (1S,13R)-10,22-dimethyl-10,22-diazahexacyclo[11.7.4.0^{1,13}.0^{3,11}.0^{4,9}.0^{14,19}]tetracosa-3(11),4(9),5,7,14(19),15,17-heptaen-16-ol::CHEMBL557937

SMILES: CN1CC[C@]23Cc4c(C[C@]2(Cc2ccc(O)cc32)C1)c1ccccc1n4C

InChI Key: InChIKey=WDTIJGFXRJTCSB-DNQXCXABSA-N

Data: 3 KI  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50296867   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50296867 ((1S,13R)-10,22-dimethyl-10,22-diazahexacyclo[11.7....) Show SMILES CN1CC[C@]23Cc4c(C[C@]2(Cc2ccc(O)cc32)C1)c1ccccc1n4C |r| Show InChI InChI=1S/C24H26N2O/c1-25-10-9-24-14-22-19(18-5-3-4-6-21(18)26(22)2)13-23(24,15-25)12-16-7-8-17(27)11-20(16)24/h3-8,11,27H,9-10,12-15H2,1-2H3/t23-,24-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 4603-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.093 BindingDB Entry DOI: 10.7270/Q2WQ04RF
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50296867 ((1S,13R)-10,22-dimethyl-10,22-diazahexacyclo[11.7....) Show SMILES CN1CC[C@]23Cc4c(C[C@]2(Cc2ccc(O)cc32)C1)c1ccccc1n4C |r| Show InChI InChI=1S/C24H26N2O/c1-25-10-9-24-14-22-19(18-5-3-4-6-21(18)26(22)2)13-23(24,15-25)12-16-7-8-17(27)11-20(16)24/h3-8,11,27H,9-10,12-15H2,1-2H3/t23-,24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	268	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 4603-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.093 BindingDB Entry DOI: 10.7270/Q2WQ04RF
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50296867 ((1S,13R)-10,22-dimethyl-10,22-diazahexacyclo[11.7....) Show SMILES CN1CC[C@]23Cc4c(C[C@]2(Cc2ccc(O)cc32)C1)c1ccccc1n4C |r| Show InChI InChI=1S/C24H26N2O/c1-25-10-9-24-14-22-19(18-5-3-4-6-21(18)26(22)2)13-23(24,15-25)12-16-7-8-17(27)11-20(16)24/h3-8,11,27H,9-10,12-15H2,1-2H3/t23-,24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]U50488 from human kappa opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 4603-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.093 BindingDB Entry DOI: 10.7270/Q2WQ04RF
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50296867 ((1S,13R)-10,22-dimethyl-10,22-diazahexacyclo[11.7....) Show SMILES CN1CC[C@]23Cc4c(C[C@]2(Cc2ccc(O)cc32)C1)c1ccccc1n4C |r| Show InChI InChI=1S/C24H26N2O/c1-25-10-9-24-14-22-19(18-5-3-4-6-21(18)26(22)2)13-23(24,15-25)12-16-7-8-17(27)11-20(16)24/h3-8,11,27H,9-10,12-15H2,1-2H3/t23-,24-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	174	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding by scintillation counting				Bioorg Med Chem Lett 19: 4603-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.093 BindingDB Entry DOI: 10.7270/Q2WQ04RF
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50296867 ((1S,13R)-10,22-dimethyl-10,22-diazahexacyclo[11.7....) Show SMILES CN1CC[C@]23Cc4c(C[C@]2(Cc2ccc(O)cc32)C1)c1ccccc1n4C |r| Show InChI InChI=1S/C24H26N2O/c1-25-10-9-24-14-22-19(18-5-3-4-6-21(18)26(22)2)13-23(24,15-25)12-16-7-8-17(27)11-20(16)24/h3-8,11,27H,9-10,12-15H2,1-2H3/t23-,24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]U50488 from human kappa opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 4603-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.093 BindingDB Entry DOI: 10.7270/Q2WQ04RF
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50296867 ((1S,13R)-10,22-dimethyl-10,22-diazahexacyclo[11.7....) Show SMILES CN1CC[C@]23Cc4c(C[C@]2(Cc2ccc(O)cc32)C1)c1ccccc1n4C |r| Show InChI InChI=1S/C24H26N2O/c1-25-10-9-24-14-22-19(18-5-3-4-6-21(18)26(22)2)13-23(24,15-25)12-16-7-8-17(27)11-20(16)24/h3-8,11,27H,9-10,12-15H2,1-2H3/t23-,24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Agonist activity at human delta opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding by scintillation counting				Bioorg Med Chem Lett 19: 4603-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.093 BindingDB Entry DOI: 10.7270/Q2WQ04RF
					More data for this Ligand-Target Pair