BDBM50296954 (Z)-5-(4-bromo-2-fluorophenyl)-3-phenylpent-2-enoic acid::CHEMBL552276

SMILES: OC(=O)\C=C(\CCc1ccc(Br)cc1F)c1ccccc1

InChI Key: InChIKey=TXZZTTXGFQGOTL-UVTDQMKNSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296954   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide dependent protein kinase-1 (Homo sapiens (Human))	BDBM50296954 ((Z)-5-(4-bromo-2-fluorophenyl)-3-phenylpent-2-enoi...) Show SMILES OC(=O)\C=C(\CCc1ccc(Br)cc1F)c1ccccc1 Show InChI InChI=1S/C17H14BrFO2/c18-15-9-8-13(16(19)11-15)6-7-14(10-17(20)21)12-4-2-1-3-5-12/h1-5,8-11H,6-7H2,(H,20,21)/b14-10-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a
Universit£tsklinikum Frankfurt Curated by ChEMBL					Assay Description Binding affinity to human PDPK1 Y288G/Q292A mutant expressed in insect cell system assessed as substrate phosphorylation by isothermal titration calo...				Nat Chem Biol 5: 758-64 (2009) Article DOI: 10.1038/nchembio.208 BindingDB Entry DOI: 10.7270/Q2V98BXR
					More data for this Ligand-Target Pair
3-phosphoinositide dependent protein kinase-1 (Homo sapiens (Human))	BDBM50296954 ((Z)-5-(4-bromo-2-fluorophenyl)-3-phenylpent-2-enoi...) Show SMILES OC(=O)\C=C(\CCc1ccc(Br)cc1F)c1ccccc1 Show InChI InChI=1S/C17H14BrFO2/c18-15-9-8-13(16(19)11-15)6-7-14(10-17(20)21)12-4-2-1-3-5-12/h1-5,8-11H,6-7H2,(H,20,21)/b14-10-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Binding affinity to PDK1 (50 to 359) by isothermal titration calorimetry				J Med Chem 52: 4683-93 (2009) Article DOI: 10.1021/jm9001499 BindingDB Entry DOI: 10.7270/Q2FB52ZC
					More data for this Ligand-Target Pair