BDBM50296956 (Z)-5-(1H-Indol-3-yl)-3-phenylpent-2-enoic Acid::CHEMBL549647

SMILES: OC(=O)\C=C(\CCc1c[nH]c2ccccc12)c1ccccc1

InChI Key: InChIKey=WTTNXKXYHDXJRU-QINSGFPZSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296956   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide dependent protein kinase-1 (Homo sapiens (Human))	BDBM50296956 ((Z)-5-(1H-Indol-3-yl)-3-phenylpent-2-enoic Acid | ...) Show SMILES OC(=O)\C=C(\CCc1c[nH]c2ccccc12)c1ccccc1 Show InChI InChI=1S/C19H17NO2/c21-19(22)12-15(14-6-2-1-3-7-14)10-11-16-13-20-18-9-5-4-8-17(16)18/h1-9,12-13,20H,10-11H2,(H,21,22)/b15-12-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Binding affinity to PDK1 (50 to 359) by isothermal titration calorimetry				J Med Chem 52: 4683-93 (2009) Article DOI: 10.1021/jm9001499 BindingDB Entry DOI: 10.7270/Q2FB52ZC
					More data for this Ligand-Target Pair