BDBM50297166 2-(3-Hydroxymethylphenylamino)benzamide::CHEMBL561596

SMILES: NC(=O)c1ccccc1Nc1cccc(CO)c1

InChI Key: InChIKey=AUSGHKHOFYDADP-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50297166   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50297166 (2-(3-Hydroxymethylphenylamino)benzamide | CHEMBL56...) Show SMILES NC(=O)c1ccccc1Nc1cccc(CO)c1 Show InChI InChI=1S/C14H14N2O2/c15-14(18)12-6-1-2-7-13(12)16-11-5-3-4-10(8-11)9-17/h1-8,16-17H,9H2,(H2,15,18)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT1 by fluorimetric analysis				Bioorg Med Chem 17: 5900-5 (2009) Article DOI: 10.1016/j.bmc.2009.07.001 BindingDB Entry DOI: 10.7270/Q24X57TQ
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50297166 (2-(3-Hydroxymethylphenylamino)benzamide | CHEMBL56...) Show SMILES NC(=O)c1ccccc1Nc1cccc(CO)c1 Show InChI InChI=1S/C14H14N2O2/c15-14(18)12-6-1-2-7-13(12)16-11-5-3-4-10(8-11)9-17/h1-8,16-17H,9H2,(H2,15,18)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT1 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b...				J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50297166 (2-(3-Hydroxymethylphenylamino)benzamide | CHEMBL56...) Show SMILES NC(=O)c1ccccc1Nc1cccc(CO)c1 Show InChI InChI=1S/C14H14N2O2/c15-14(18)12-6-1-2-7-13(12)16-11-5-3-4-10(8-11)9-17/h1-8,16-17H,9H2,(H2,15,18)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b...				J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS
					More data for this Ligand-Target Pair