BDBM50297167 2-[3-(2-Hydroxylethyl)phenylamino]benzamide::CHEMBL572123

SMILES: NC(=O)c1ccccc1Nc1cccc(CCO)c1

InChI Key: InChIKey=ZCCGBAKTMUSIEK-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50297167   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-Dependent Deacetylase Sirtuin-1 (Homo sapiens (Human))	BDBM50297167 (2-[3-(2-Hydroxylethyl)phenylamino]benzamide | CHEM...) Show SMILES NC(=O)c1ccccc1Nc1cccc(CCO)c1 Show InChI InChI=1S/C15H16N2O2/c16-15(19)13-6-1-2-7-14(13)17-12-5-3-4-11(10-12)8-9-18/h1-7,10,17-18H,8-9H2,(H2,16,19)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT1 by fluorimetric analysis				Bioorg Med Chem 17: 5900-5 (2009) Article DOI: 10.1016/j.bmc.2009.07.001 BindingDB Entry DOI: 10.7270/Q24X57TQ
					More data for this Ligand-Target Pair
NAD-Dependent Deacetylase Sirtuin-1 (Homo sapiens (Human))	BDBM50297167 (2-[3-(2-Hydroxylethyl)phenylamino]benzamide | CHEM...) Show SMILES NC(=O)c1ccccc1Nc1cccc(CCO)c1 Show InChI InChI=1S/C15H16N2O2/c16-15(19)13-6-1-2-7-14(13)17-12-5-3-4-11(10-12)8-9-18/h1-7,10,17-18H,8-9H2,(H2,16,19)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT1 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b...				J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS
					More data for this Ligand-Target Pair
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human))	BDBM50297167 (2-[3-(2-Hydroxylethyl)phenylamino]benzamide | CHEM...) Show SMILES NC(=O)c1ccccc1Nc1cccc(CCO)c1 Show InChI InChI=1S/C15H16N2O2/c16-15(19)13-6-1-2-7-14(13)17-12-5-3-4-11(10-12)8-9-18/h1-7,10,17-18H,8-9H2,(H2,16,19)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b...				J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS
					More data for this Ligand-Target Pair