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BDBM50297469 CHEMBL552423::N-(1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)-2-oxoindolin-6-yl)propionamide

SMILES: CCC(=O)Nc1ccc2C(N=O)C(=O)N(Cc3cc(F)cc4COCOc34)c2c1

InChI Key: InChIKey=CYMSMBQNHAQGPJ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297469   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 10


(Homo sapiens (human))
BDBM50297469
PNG
(CHEMBL552423 | N-(1-((6-fluoro-4H-benzo[d][1,3]dio...)
Show SMILES CCC(=O)Nc1ccc2C(N=O)C(=O)N(Cc3cc(F)cc4COCOc34)c2c1
Show InChI InChI=1S/C20H18FN3O5/c1-2-17(25)22-14-3-4-15-16(7-14)24(20(26)18(15)23-27)8-11-5-13(21)6-12-9-28-10-29-19(11)12/h3-7,18H,2,8-10H2,1H3,(H,22,25)
PDB
MMDB

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Patents


Similars

Article
PubMed
610n/an/an/an/an/an/an/an/a



Vertex Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of JNK3 by spectrophotometric coupled enzyme assay


Bioorg Med Chem Lett 19: 2891-5 (2009)

More data for this
Ligand-Target Pair