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BDBM50297475 1-(3,5-dimethoxybenzyl)-3-(hydroxyimino)indolin-2-one::CHEMBL550534

SMILES: COc1cc(CN2C(=O)C(N=O)c3ccccc23)cc(OC)c1

InChI Key: InChIKey=NXABZZPVCHWXIM-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297475   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 10


(Homo sapiens (human))
BDBM50297475
PNG
(1-(3,5-dimethoxybenzyl)-3-(hydroxyimino)indolin-2-...)
Show SMILES COc1cc(CN2C(=O)C(N=O)c3ccccc23)cc(OC)c1
Show InChI InChI=1S/C17H16N2O4/c1-22-12-7-11(8-13(9-12)23-2)10-19-15-6-4-3-5-14(15)16(18-21)17(19)20/h3-9,16H,10H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
990n/an/an/an/an/an/an/an/a



Vertex Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of JNK3 by spectrophotometric coupled enzyme assay


Bioorg Med Chem Lett 19: 2891-5 (2009)

More data for this
Ligand-Target Pair