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BDBM50297478 5-fluoro-3-(hydroxyimino)-1-(4-methoxybenzyl)indolin-2-one::CHEMBL564745

SMILES: COc1ccc(CN2C(=O)C(N=O)c3cc(F)ccc23)cc1

InChI Key: InChIKey=NRGHJPXGJNCGQR-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297478   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 10


(Homo sapiens (Human))
BDBM50297478
PNG
(5-fluoro-3-(hydroxyimino)-1-(4-methoxybenzyl)indol...)
Show SMILES COc1ccc(CN2C(=O)C(N=O)c3cc(F)ccc23)cc1
Show InChI InChI=1S/C16H13FN2O3/c1-22-12-5-2-10(3-6-12)9-19-14-7-4-11(17)8-13(14)15(18-21)16(19)20/h2-8,15H,9H2,1H3
PDB
MMDB

NCI pathway
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PC cid
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Patents

Article
PubMed
1.60E+3n/an/an/an/an/an/an/an/a



Vertex Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of JNK3 by spectrophotometric coupled enzyme assay


Bioorg Med Chem Lett 19: 2891-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.043
More data for this
Ligand-Target Pair