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BDBM50297483 3-(hydroxyimino)-5-methyl-1-(3-(trifluoromethyl)benzyl)indolin-2-one::CHEMBL559351

SMILES: Cc1ccc2N(Cc3cccc(c3)C(F)(F)F)C(=O)C(N=O)c2c1

InChI Key: InChIKey=MTHLUZKAMVJIRU-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297483   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 10


(Homo sapiens (Human))
BDBM50297483
PNG
(3-(hydroxyimino)-5-methyl-1-(3-(trifluoromethyl)be...)
Show SMILES Cc1ccc2N(Cc3cccc(c3)C(F)(F)F)C(=O)C(N=O)c2c1
Show InChI InChI=1S/C17H13F3N2O2/c1-10-5-6-14-13(7-10)15(21-24)16(23)22(14)9-11-3-2-4-12(8-11)17(18,19)20/h2-8,15H,9H2,1H3
PDB
MMDB

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Patents

Article
PubMed
2.70E+3n/an/an/an/an/an/an/an/a



Vertex Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of JNK3 by spectrophotometric coupled enzyme assay


Bioorg Med Chem Lett 19: 2891-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.043
BindingDB Entry DOI: 10.7270/Q2F76CMZ
More data for this
Ligand-Target Pair