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BDBM50297494 3-(hydroxyimino)-1-(4-methylbenzyl)indolin-2-one::CHEMBL540228

SMILES: Cc1ccc(CN2C(=O)C(N=O)c3ccccc23)cc1

InChI Key: InChIKey=VEKWHUILUUJNCV-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297494   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 10


(Homo sapiens (Human))
BDBM50297494
PNG
(3-(hydroxyimino)-1-(4-methylbenzyl)indolin-2-one |...)
Show SMILES Cc1ccc(CN2C(=O)C(N=O)c3ccccc23)cc1
Show InChI InChI=1S/C16H14N2O2/c1-11-6-8-12(9-7-11)10-18-14-5-3-2-4-13(14)15(17-20)16(18)19/h2-9,15H,10H2,1H3
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MMDB

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Article
PubMed
9.90E+3n/an/an/an/an/an/an/an/a



Vertex Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of JNK3 by spectrophotometric coupled enzyme assay


Bioorg Med Chem Lett 19: 2891-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.043
BindingDB Entry DOI: 10.7270/Q2F76CMZ
More data for this
Ligand-Target Pair