BDBM50297624 1-phenyl-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxamide::CHEMBL550068

SMILES: FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)N2CCn3cccc3C2c2ccccc2)c1

InChI Key: InChIKey=PSCSTQNZPOWDJA-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50297624   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50297624 (1-phenyl-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-p...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)N2CCn3cccc3C2c2ccccc2)c1 Show InChI InChI=1S/C31H32F3N5O/c32-31(33,34)25-8-10-27(11-9-25)38-18-12-23(22-38)21-36-16-13-26(14-17-36)35-30(40)39-20-19-37-15-4-7-28(37)29(39)24-5-2-1-3-6-24/h1-12,15,18,22,26,29H,13-14,16-17,19-21H2,(H,35,40)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50297624 (1-phenyl-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-p...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)N2CCn3cccc3C2c2ccccc2)c1 Show InChI InChI=1S/C31H32F3N5O/c32-31(33,34)25-8-10-27(11-9-25)38-18-12-23(22-38)21-36-16-13-26(14-17-36)35-30(40)39-20-19-37-15-4-7-28(37)29(39)24-5-2-1-3-6-24/h1-12,15,18,22,26,29H,13-14,16-17,19-21H2,(H,35,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in CHO cells by patch-clamp assay				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50297624 (1-phenyl-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-p...) Show SMILES FC(F)(F)c1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)N2CCn3cccc3C2c2ccccc2)c1 Show InChI InChI=1S/C31H32F3N5O/c32-31(33,34)25-8-10-27(11-9-25)38-18-12-23(22-38)21-36-16-13-26(14-17-36)35-30(40)39-20-19-37-15-4-7-28(37)29(39)24-5-2-1-3-6-24/h1-12,15,18,22,26,29H,13-14,16-17,19-21H2,(H,35,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP3A4 after 45 mins				Bioorg Med Chem Lett 19: 4274-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.066 BindingDB Entry DOI: 10.7270/Q24Q7V1J
					More data for this Ligand-Target Pair