null

SMILES: CS(=O)(=O)c1ccc(cc1)-c1cnc(Nc2ccccc2)nc1-c1ccc(F)cc1

InChI Key: InChIKey=VOUVVXFHPYNZOA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297697   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50297697 (4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-N-...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc(Nc2ccccc2)nc1-c1ccc(F)cc1 Show InChI InChI=1S/C23H18FN3O2S/c1-30(28,29)20-13-9-16(10-14-20)21-15-25-23(26-19-5-3-2-4-6-19)27-22(21)17-7-11-18(24)12-8-17/h2-15H,1H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...				Bioorg Med Chem Lett 19: 4509-14 (2009) Article DOI: 10.1016/j.bmcl.2009.02.089 BindingDB Entry DOI: 10.7270/Q2W66KSC
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50297697 (4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-N-...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc(Nc2ccccc2)nc1-c1ccc(F)cc1 Show InChI InChI=1S/C23H18FN3O2S/c1-30(28,29)20-13-9-16(10-14-20)21-15-25-23(26-19-5-3-2-4-6-19)27-22(21)17-7-11-18(24)12-8-17/h2-15H,1H3,(H,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human COX1 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...				Bioorg Med Chem Lett 19: 4509-14 (2009) Article DOI: 10.1016/j.bmcl.2009.02.089 BindingDB Entry DOI: 10.7270/Q2W66KSC
					More data for this Ligand-Target Pair