BDBM50297748 (R)-3-(2-hydroxyphenylamino)-4-(1-(5-methylfuran-2-yl)propylamino)cyclobut-3-ene-1,2-dione::CHEMBL551747

SMILES: CC[C@@H](Nc1c(Nc2ccccc2O)c(=O)c1=O)c1ccc(C)o1

InChI Key: InChIKey=XFBQXPPIRNKFRW-LLVKDONJSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297748   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50297748 ((R)-3-(2-hydroxyphenylamino)-4-(1-(5-methylfuran-2...) Show SMILES CC[C@@H](Nc1c(Nc2ccccc2O)c(=O)c1=O)c1ccc(C)o1 |r| Show InChI InChI=1S/C18H18N2O4/c1-3-11(14-9-8-10(2)24-14)19-15-16(18(23)17(15)22)20-12-6-4-5-7-13(12)21/h4-9,11,19-21H,3H2,1-2H3/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of human [125I]IL-8 from human CXCR2				Bioorg Med Chem Lett 19: 4446-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.049 BindingDB Entry DOI: 10.7270/Q2H1323X
					More data for this Ligand-Target Pair