BDBM50297763 (R)-4-(3,4-dioxo-2-(1-phenylpropylamino)cyclobut-1-enylamino)-3-hydroxy-N,N-dimethylbiphenyl-2-carboxamide::CHEMBL557877

SMILES: CC[C@@H](Nc1c(Nc2ccc(-c3ccccc3)c(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccccc1

InChI Key: InChIKey=QBIWDFKNXJRTFF-HXUWFJFHSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297763   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50297763 ((R)-4-(3,4-dioxo-2-(1-phenylpropylamino)cyclobut-1...) Show SMILES CC[C@@H](Nc1c(Nc2ccc(-c3ccccc3)c(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccccc1 |r| Show InChI InChI=1S/C28H27N3O4/c1-4-20(18-13-9-6-10-14-18)29-23-24(27(34)26(23)33)30-21-16-15-19(17-11-7-5-8-12-17)22(25(21)32)28(35)31(2)3/h5-16,20,29-30,32H,4H2,1-3H3/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of human [125I]IL-8 from human CXCR2				Bioorg Med Chem Lett 19: 4446-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.049 BindingDB Entry DOI: 10.7270/Q2H1323X
					More data for this Ligand-Target Pair