BDBM50297817 4-(2-propoxyethyl)-6-(pyridin-4-yl)-2-((tetrahydro-2H-pyran-4-yl)methylamino)pyrido[2,3-b]pyrazin-3(4H)-one::CHEMBL561088

SMILES: CCCOCCn1c2nc(ccc2nc(NCC2CCOCC2)c1=O)-c1ccncc1

InChI Key: InChIKey=WFHWZZABOMLYBG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297817   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50297817 (4-(2-propoxyethyl)-6-(pyridin-4-yl)-2-((tetrahydro...) Show SMILES CCCOCCn1c2nc(ccc2nc(NCC2CCOCC2)c1=O)-c1ccncc1 Show InChI InChI=1S/C23H29N5O3/c1-2-12-30-15-11-28-22-20(4-3-19(27-22)18-5-9-24-10-6-18)26-21(23(28)29)25-16-17-7-13-31-14-8-17/h3-6,9-10,17H,2,7-8,11-16H2,1H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of PDE5				Bioorg Med Chem Lett 19: 4088-91 (2009) Article DOI: 10.1016/j.bmcl.2009.06.012 BindingDB Entry DOI: 10.7270/Q23R0SXR
					More data for this Ligand-Target Pair