BDBM50298000 (+/-)-5-(2,3,5-trifluorophenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid::CHEMBL558463

SMILES: OC(=O)c1n[nH]c2CCC(Cc12)c1cc(F)cc(F)c1F

InChI Key: InChIKey=DKRWTSSIUWFPPD-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50298000   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50298000 ((+/-)-5-(2,3,5-trifluorophenyl)-4,5,6,7-tetrahydro...) Show SMILES OC(=O)c1n[nH]c2CCC(Cc12)c1cc(F)cc(F)c1F Show InChI InChI=1S/C14H11F3N2O2/c15-7-4-8(12(17)10(16)5-7)6-1-2-11-9(3-6)13(14(20)21)19-18-11/h4-6H,1-3H2,(H,18,19)(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 19: 4768-72 (2009) Article DOI: 10.1016/j.bmcl.2009.06.054 BindingDB Entry DOI: 10.7270/Q2M909M3
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50298000 ((+/-)-5-(2,3,5-trifluorophenyl)-4,5,6,7-tetrahydro...) Show SMILES OC(=O)c1n[nH]c2CCC(Cc12)c1cc(F)cc(F)c1F Show InChI InChI=1S/C14H11F3N2O2/c15-7-4-8(12(17)10(16)5-7)6-1-2-11-9(3-6)13(14(20)21)19-18-11/h4-6H,1-3H2,(H,18,19)(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serum				Bioorg Med Chem Lett 19: 4768-72 (2009) Article DOI: 10.1016/j.bmcl.2009.06.054 BindingDB Entry DOI: 10.7270/Q2M909M3
					More data for this Ligand-Target Pair