BDBM50298374 CHEMBL577150::N,N'-[4,5-Acridindiylbis(methylene)]bis[3-(1-pyrrolidinyl)propanamide]

SMILES: O=C(CCN1CCCC1)NCc1cccc2cc3cccc(CNC(=O)CCN4CCCC4)c3nc12

InChI Key: InChIKey=NOCHRQUOQDWJPE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50298374   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50298374 (CHEMBL577150 | N,N'-[4,5-Acridindiylbis(methylene)...) Show SMILES O=C(CCN1CCCC1)NCc1cccc2cc3cccc(CNC(=O)CCN4CCCC4)c3nc12 Show InChI InChI=1S/C29H37N5O2/c35-26(11-17-33-13-1-2-14-33)30-20-24-9-5-7-22-19-23-8-6-10-25(29(23)32-28(22)24)21-31-27(36)12-18-34-15-3-4-16-34/h5-10,19H,1-4,11-18,20-21H2,(H,30,35)(H,31,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Reims-Champagne-Ardenne Curated by ChEMBL					Assay Description Inhibition of human telomerase in A549 cells by TRAP assay				Eur J Med Chem 44: 3880-8 (2009) Article DOI: 10.1016/j.ejmech.2009.04.021 BindingDB Entry DOI: 10.7270/Q2W37WDH
					More data for this Ligand-Target Pair