BDBM50298377 CHEMBL576188::N,N'-[4,5-Acridindiylbis(methylene)]bis[4-(1-piperidinyl)butanamide]

SMILES: O=C(CCCN1CCCCC1)NCc1cccc2cc3cccc(CNC(=O)CCCN4CCCCC4)c3nc12

InChI Key: InChIKey=GQRJHPWTSHKLBR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50298377   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50298377 (CHEMBL576188 | N,N'-[4,5-Acridindiylbis(methylene)...) Show SMILES O=C(CCCN1CCCCC1)NCc1cccc2cc3cccc(CNC(=O)CCCN4CCCCC4)c3nc12 Show InChI InChI=1S/C33H45N5O2/c39-30(15-9-21-37-17-3-1-4-18-37)34-24-28-13-7-11-26-23-27-12-8-14-29(33(27)36-32(26)28)25-35-31(40)16-10-22-38-19-5-2-6-20-38/h7-8,11-14,23H,1-6,9-10,15-22,24-25H2,(H,34,39)(H,35,40)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Reims-Champagne-Ardenne Curated by ChEMBL					Assay Description Inhibition of human telomerase in A549 cells by TRAP assay				Eur J Med Chem 44: 3880-8 (2009) Article DOI: 10.1016/j.ejmech.2009.04.021 BindingDB Entry DOI: 10.7270/Q2W37WDH
					More data for this Ligand-Target Pair