BDBM50298953 CHEMBL574032::N-[2-(3,4-Dichlorophenyl)ethyl]1-(2,4-dichlorophenyl)-5-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methyl-1H-pyrazole-3-carboxamide

SMILES: Cc1ccc(C)n1-c1c(C)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NCCc1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=JNVQWCOBTNAZDC-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50298953   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50298953 (CHEMBL574032 | N-[2-(3,4-Dichlorophenyl)ethyl]1-(2...) Show SMILES Cc1ccc(C)n1-c1c(C)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NCCc1ccc(Cl)c(Cl)c1 |(4.67,-7.31,;5.6,-6.07,;7.14,-6.08,;7.62,-4.62,;6.38,-3.7,;6.39,-2.16,;5.13,-4.6,;3.67,-4.11,;3.2,-2.64,;4.11,-1.4,;1.65,-2.62,;1.17,-4.09,;2.41,-5.01,;2.4,-6.55,;3.73,-7.34,;3.72,-8.88,;2.38,-9.64,;2.37,-11.18,;1.05,-8.86,;1.06,-7.32,;-.27,-6.53,;.76,-1.37,;1.39,.03,;-.78,-1.52,;-1.68,-.27,;-3.21,-.41,;-4.11,.84,;-3.48,2.24,;-4.38,3.49,;-5.91,3.35,;-6.8,4.6,;-6.55,1.94,;-8.08,1.79,;-5.65,.69,)| Show InChI InChI=1S/C25H22Cl4N4O/c1-14-4-5-15(2)32(14)25-16(3)23(31-33(25)22-9-7-18(26)13-21(22)29)24(34)30-11-10-17-6-8-19(27)20(28)12-17/h4-9,12-13H,10-11H2,1-3H3,(H,30,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK cells				Bioorg Med Chem 17: 5549-64 (2009) Article DOI: 10.1016/j.bmc.2009.06.027 BindingDB Entry DOI: 10.7270/Q2XK8GHD
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50298953 (CHEMBL574032 | N-[2-(3,4-Dichlorophenyl)ethyl]1-(2...) Show SMILES Cc1ccc(C)n1-c1c(C)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NCCc1ccc(Cl)c(Cl)c1 |(4.67,-7.31,;5.6,-6.07,;7.14,-6.08,;7.62,-4.62,;6.38,-3.7,;6.39,-2.16,;5.13,-4.6,;3.67,-4.11,;3.2,-2.64,;4.11,-1.4,;1.65,-2.62,;1.17,-4.09,;2.41,-5.01,;2.4,-6.55,;3.73,-7.34,;3.72,-8.88,;2.38,-9.64,;2.37,-11.18,;1.05,-8.86,;1.06,-7.32,;-.27,-6.53,;.76,-1.37,;1.39,.03,;-.78,-1.52,;-1.68,-.27,;-3.21,-.41,;-4.11,.84,;-3.48,2.24,;-4.38,3.49,;-5.91,3.35,;-6.8,4.6,;-6.55,1.94,;-8.08,1.79,;-5.65,.69,)| Show InChI InChI=1S/C25H22Cl4N4O/c1-14-4-5-15(2)32(14)25-16(3)23(31-33(25)22-9-7-18(26)13-21(22)29)24(34)30-11-10-17-6-8-19(27)20(28)12-17/h4-9,12-13H,10-11H2,1-3H3,(H,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.94E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK cells				Bioorg Med Chem 17: 5549-64 (2009) Article DOI: 10.1016/j.bmc.2009.06.027 BindingDB Entry DOI: 10.7270/Q2XK8GHD
					More data for this Ligand-Target Pair