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SMILES: COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(=O)NO

InChI Key: InChIKey=OREDIHYKGISTDR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50299059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50299059 (CHEMBL573934 | N-Hydroxy-2-(4'-methoxybiphenyl-4-y...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(=O)NO Show InChI InChI=1S/C20H17NO5S/c1-26-16-10-6-14(7-11-16)15-8-12-17(13-9-15)27(24,25)19-5-3-2-4-18(19)20(22)21-23/h2-13,23H,1H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant pro-MMP14 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50299059 (CHEMBL573934 | N-Hydroxy-2-(4'-methoxybiphenyl-4-y...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(=O)NO Show InChI InChI=1S/C20H17NO5S/c1-26-16-10-6-14(7-11-16)15-8-12-17(13-9-15)27(24,25)19-5-3-2-4-18(19)20(22)21-23/h2-13,23H,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50299059 (CHEMBL573934 | N-Hydroxy-2-(4'-methoxybiphenyl-4-y...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(=O)NO Show InChI InChI=1S/C20H17NO5S/c1-26-16-10-6-14(7-11-16)15-8-12-17(13-9-15)27(24,25)19-5-3-2-4-18(19)20(22)21-23/h2-13,23H,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50299059 (CHEMBL573934 | N-Hydroxy-2-(4'-methoxybiphenyl-4-y...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(=O)NO Show InChI InChI=1S/C20H17NO5S/c1-26-16-10-6-14(7-11-16)15-8-12-17(13-9-15)27(24,25)19-5-3-2-4-18(19)20(22)21-23/h2-13,23H,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50299059 (CHEMBL573934 | N-Hydroxy-2-(4'-methoxybiphenyl-4-y...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(=O)NO Show InChI InChI=1S/C20H17NO5S/c1-26-16-10-6-14(7-11-16)15-8-12-17(13-9-15)27(24,25)19-5-3-2-4-18(19)20(22)21-23/h2-13,23H,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP1 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50299059 (CHEMBL573934 | N-Hydroxy-2-(4'-methoxybiphenyl-4-y...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(=O)NO Show InChI InChI=1S/C20H17NO5S/c1-26-16-10-6-14(7-11-16)15-8-12-17(13-9-15)27(24,25)19-5-3-2-4-18(19)20(22)21-23/h2-13,23H,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Matrix metalloproteinase-16 (Homo sapiens (Human))	BDBM50299059 (CHEMBL573934 | N-Hydroxy-2-(4'-methoxybiphenyl-4-y...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(=O)NO Show InChI InChI=1S/C20H17NO5S/c1-26-16-10-6-14(7-11-16)15-8-12-17(13-9-15)27(24,25)19-5-3-2-4-18(19)20(22)21-23/h2-13,23H,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50299059 (CHEMBL573934 | N-Hydroxy-2-(4'-methoxybiphenyl-4-y...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(=O)NO Show InChI InChI=1S/C20H17NO5S/c1-26-16-10-6-14(7-11-16)15-8-12-17(13-9-15)27(24,25)19-5-3-2-4-18(19)20(22)21-23/h2-13,23H,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of trypsin activated human pro-MMP3 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50299059 (CHEMBL573934 | N-Hydroxy-2-(4'-methoxybiphenyl-4-y...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(=O)NO Show InChI InChI=1S/C20H17NO5S/c1-26-16-10-6-14(7-11-16)15-8-12-17(13-9-15)27(24,25)19-5-3-2-4-18(19)20(22)21-23/h2-13,23H,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair