BDBM50299072 2-Methyl-5-{3-[4-(methylsulfinyl)phenyl]-1-benzofuran-5-yl}-1,3,4-thiadiazole::CHEMBL572793

SMILES: Cc1nnc(s1)-c1ccc2occ(-c3ccc(cc3)S(C)=O)c2c1

InChI Key: InChIKey=PHTBTRWABMBCBU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299072   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50299072 (2-Methyl-5-{3-[4-(methylsulfinyl)phenyl]-1-benzofu...) Show SMILES Cc1nnc(s1)-c1ccc2occ(-c3ccc(cc3)S(C)=O)c2c1 Show InChI InChI=1S/C18H14N2O2S2/c1-11-19-20-18(23-11)13-5-8-17-15(9-13)16(10-22-17)12-3-6-14(7-4-12)24(2)21/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3-beta				J Med Chem 52: 6270-86 (2009) Article DOI: 10.1021/jm900647e BindingDB Entry DOI: 10.7270/Q2CZ377V
					More data for this Ligand-Target Pair